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Prevalence of asymptomatic intracranial atherosclerosis in high-risk patients.

Wong KS, Ng PW, Tang A, Liu R, Yeung V, Tomlinson B

Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. ks-wong@cuhk.edu.hk

We used transcranial Doppler to screen 3,057 patients who had at least one vascular risk factor of hypertension, diabetes, or hyperlipidemia and found 385 (12.6%) had middle cerebral artery stenosis. Elderly, hypertension, diabetes, and hyperlipidemia were associated factors. The prevalence escalated quadratically with increasing number of associated factors: from 7.2% for one, to 29.6% for four associated factors. Asymptomatic middle cerebral artery stenosis is common in patients with vascular risk factors.

Published 5 June 2007 in Neurology, 68(23): 2035-8.
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