Hypertension Research Today is a free monthly online journal that collates and summarizes the latest research about Hypertension, including details on symptoms, diagnosis, diet, treatment, causes.

Therapeutic interventions for hypertension in metabolic syndrome: a comprehensive approach.

Ganne S, Arora S, Karam J, McFarlane SI

State University of New York, Division of Endocrinology, Diabetes and Hypertension, Downstate Medical Center, Brooklyn, NY, USA. sudha_ganne@hotmail.com

Hypertension is a major component of the metabolic syndrome and a major cardiovascular risk factor. Both disorders are rapidly increasing in frequency, with hypertension affecting nearly 60 million Americans and over 1 billion people worldwide, and metabolic syndrome affecting 44% of the US population above the age of 60 years. Sedentary lifestyle, together with obesity and aging of the population, are the major contributing factors for this growing epidemic. Hypertension in metabolic syndrome possesses unique pathophysiological aspects that have considerable implications on therapy of this disease. In this article, we review the pathophysiology and provide a rationale for the current therapeutic options in light of the most recent clinical trials in the field.

Published 6 March 2007 in Expert Rev Cardiovasc Ther, 5(2): 201-11.
Full-text of this article is available online (may require subscription).

© 2004-2008 Hypertension Research Today. All Rights Reserved.