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Mixed cranial nerve neuroma revealing itself as baroreflex failure.

Guasti L, Simoni C, Scamoni C, Sarzi Braga S, Crespi C, Cimpanelli M, Gaudio G, Pedretti R, Mainardi LT, Grandi AM, Tomei G, Venco A

Internal Medicine, Department of Clinical Medicine-University of Insubria, Ospedale di Circolo Viale Borri 57, 21100 Varese, Italy. luigina.guasti@uninsubria.it

We report here the first case of baroreflex failure due to a mixed cranial nerve neuroma in which the clinical manifestations (recurrent severe hypertensive crisis, hypotension) due to baroreflex arc impairment preceded the clinical diagnosis of brain tumour and neurosurgery by a few months. Given the clinical suspicion of baroreflex failure, even in the absence of iatrogenic clues, we propose that the patient's study should include neuroradiologic evaluation of the ponto-cerebellar angulus.

Published 20 November 2006 in Auton Neurosci, 130(1): 57-60.
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